Most tentative scientific abstract ever
- Most tentative scientific abstract ever ››
- Hake and Allis begin
The hypothesis is interesting and almost certainly "not correct in every detail". But that's okay: why so apologetic-in-anticipation?In the history of science, provocative but, at times, controversial ideas have been put forward to explain basic problems that confront and intrigue the scientific community. These hypotheses, although often not correct in every detail, lead to increased discussion that ultimately guides experimental tests of the principal concepts and produce valuable insights into long-standing questions. Here, we present a hypothesis, the "H3 barcode hypothesis." Hopefully, our ideas will evoke critical discussion and new experimental approaches that bear on general topics, such as nuclear architecture, epigenetic memory, and cell-fate choice.
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